Approximately 350 million people worldwide have arthritis. Pretty shocking, given the fact that these statistics don’t even include the individuals who aren’t officially diagnosed.
So what can cannabis for arthritis achieve with a disease that most people take pain meds for? Well, quite a lot, actually. But first, we need to learn a little bit more about arthritis, and what it means for those who have it.
What is Arthritis?
Contrary to popular belief, arthritis isn’t just one single disease. It is essentially an informal way of referring to chronic inflammation, joint pain, or joint disease. In fact, there are more than 100 different types of arthritis, and anyone of any age, race and/or sex can experience them.
Types of arthritis can include:
– Back pain
– Bursitis
– Carpal Tunnel Syndrome
– Chronic Fatigue Syndrome
– Fibromyalgia
– Gout
– Inflammatory Bowel Disease
– Lupus
– Lyme Disease
– Pagets
– Scleroderma
– Spinal Stenosis
While arthritis is incredibly common, it still remains a very misunderstood disease. It is so broad, that its classification literally means “inflammation of one or more joints.” You could pretty much put that classification on just about any disease.
Arthritis symptoms may come and go, and they can be mild, moderate or severe. They may stay the same for years, but then progress and get worse over time. If neglected for long enough, arthritis can inflict irreparable damage over time, and result in long or short-term disability and inability to perform basic functions like walking or climbing stairs.
Arthritis likes to settle in weight-bearing joints like the hips, knees and spine, but it can also afflict non-weight-bearing joints such as those in the fingers.
Cannabis for Arthritis
Given that arthritis is an inflammatory condition, and cannabis beats inflammation, it is not that surprising that people are turning to cannabis for arthritis relief.
Within each and every one of us lays a system called the endocannabinoid system (ECS). The main receptors of this system are CB1 and CB2. CB1 receptors are mostly located in the nervous system, connective tissues, gonads, glands and organs. CB2 receptors take reign over the rest of our body, and are primarily found in the immune system. However, they’re also found in the spleen, liver, heart, kidneys, bones, blood vessels, lymph cells, endocrine glands, and reproductive organs (1).
Our body naturally produces endocannabinoids that stimulate and modulate these two receptors. Similarly, cannabis contains phytocannabinoids (like THC and CBD) that are closely related and molecularly similar to endocannabinoids. These phytocannabinoids also interact and modulate the CB1 and CB2 receptors, which produces a wide range of physiological effects.
A study published in the journal Rheumatology from Dr. Sheng-Ming Dai of China’s Second Military Medical University found that CB2 receptors are found in unusually high levels in the joint tissue of arthritis patients (2). This led the researchers to conclude that cannabis is key to activating those receptors, thus reducing pain and inflammation.
In 2008, a review concluded that CBD reduced pain associated with rheumatoid arthritis (3), and also improved sleep quality for patients without any negative side effects. Another study from 2017 found that CBD could be a safe and useful treatment for osteoarthritis joint pain (4).
Because cannabis is still illegal across much of America, and other countries, clinical studies carried out on actual human beings is lacking. This is slowly changing, however, as some countries, like Canada, have started legalizing the medicinal plant. As a result, more studies are taking place. In the meantime, we just need to wait (or simply trust how our own bodies feel when medicating with cannabis).
Repairing Damage to Arthritic Joints with Cannabis
Canadian researcher Dr. Jason McDougall, a professor of pharmacology and anesthesia at Dalhousie University in Halifax, has undertaken a new study to find out if medical marijuana can help repair arthritic joints and relieve pain. The study, supported by the Arthritis Society of Canada, was given a grant for a comprehensive, three-year study to investigate if cannabis repairs the joints by fighting inflammation, or if it is simply just dampening the pain response in the brain.
President and CEO of The Arthritis Society, Janice Yale, stated that (5):
People living with arthritis pain are looking for alternatives to improve their quality of life. We need research to help answer the many important questions about medical cannabis and its use. Our goal is to give Canadians the ability to make informed choices about their treatment options and to give physicians evidence-based guidelines to make treatment recommendations for their patients. This project is an important step to achieving those goals.
McDougall told CBC Radio’s Information Morning the following when asked to describe the nerves of an arthritis sufferer:
The nerves are like wires that have been stripped of their coating. They’re all bare, they’re all raw and responsible for feeling a lot of pain. What we hypothesize is that by locally administering these cannabis-like molecules to those nerves, we’d actually be able to repair them and reduce the pain of arthritis.
McDougall’s findings have so far shown that cannabis molecules can attach themselves to nerve receptors and control the firing of pain signals in the joint.
Another study published in the journal of Philosophical Transactions of the Royal Society B found that the body’s endocannabinoid system releases antioxidants that help repair damaged cells when it becomes triggered by outside cannabinoids (6).
The evidence seems compelling enough for anyone to trust that cannabis really does help those suffering from arthritic conditions. Some individuals have even gone as far as juicing raw cannabis to help alleviate their arthritis. The results? Inspiring to say the least.
Juicing Raw Cannabis for Arthritis
McDougall’s preliminary findings have actually been proven in some anecdotal circumstances. Take Katie Marsh from Maine, a sufferer of rheumatoid arthritis who was on prescription prednisone and antibiotics for years before she discovered cannabis. Her doctors encouraged her to take disease-modifying anti-rheumatic drugs (DMARDS), but the side effects were so intense that she finally decided to seek out the advice of a physician who specialized in dietary cannabis.
After speaking with the physician, Marsh began juicing raw cannabis and blending it into smoothies. She also consumed the whole plant, raw. The results she experienced were immediate. Within just a few days, Marsh went off prednisone and pain killers. After just 11 months of regular cannabis juicing, Marsh’s condition went into remission.
THC or CBD?
Cannabis contains both CBD and THC, but they differ from one another in that THC is psychoactive (gets you “high”), and CBD is non-psychoactive (doesn’t get you “high”).
As for which one works best with arthritis, both come with their own benefits. Both CBD and THC are useful for relieving inflammation in the body, but some people might prefer CBD as it doesn’t come with psychoactive effects.
CBD is particularly desirable for those with specific autoimmune conditions, as it works to enhance and improve the state of ones immune system.
CBD bonds best with CB2 receptors, making it easier to battle inflammation in the joints, whereas THC bonds best to CB1 receptors to give individuals relief from chronic pain. It is also good for anxiety and depression, two conditions that often plague the minds of those with debilitating conditions like arthritis. If choosing a THC strand of cannabis – go for indica over sativa, as it calms and relaxes the body more than stimulating the creative mind (that is, unless, you’re feeling a little creative).
Valarie Schofield says
I’m 80 years young. I DO BELIEVE IN CANNABIS. Wish there was a way for me to take part IN ANY CANNABIS STUDY. I live in Georgia but am willing to travel just about ANYWHERE. I get around quite well by myself including driving. I’ve been diagnosed with osteoarthritis. Some pain in knees and hands. I plan to be around for many more years to come. H E L P !
Mary. says
I know for sure it will do wonders. I Managed by chance to get some Transdermal slow release patches, I didn’t think it could work, been on soo many meds over the years. They last 12 hours stick patch on I the morning off 12 hours later for bed. Magic. ?? P.S. Am 82 yr old.
Carly Fraser says
So glad to hear they are working for you! 🙂
Bianca says
Where did you get your transdermal patches?
Carly Fraser says
Mary’s Medicinals sells them: https://marysmedicinals.com/product/transdermal-patch/
Nancy M says
I have Rheumatoid Arthritis and take biologic injections and Methotrexate. I am moving to a country where I wil no longer be able to financially access these. How much CBD should I take and in what form? Thank you, Nancy
Carly Fraser says
If you’re suffering from arthritis, look for something that is at least 1000-2000 mg/mL. I would take amounts according to what is suggested as a serving size on the bottle, and if it doesn’t work, then up the dose until it does. Take it in oil form. Hold it under your tongue for 30 seconds before swallowing.
Johnnie Judy says
Most bottles of CBD oil says a serving is 20 drops, if you have a good pure oil that is usually to much. You should start low and slow to find the right amount your body needs. Your body can only use so much CBD at once, it’s a set absorption rate so once you get above 1000mg that extra CBD is basically being wasted. Do research on CBD oils before starting. Other than prescription CBD. The are only 15 companies that are Hemp Authority Certified
Mr thomas says
I’m from uk , l have been told by nhs doctor that the whole knee will needs to be replaced soon as possible . But I refused it, and told the doctor I was trying thc +cvd . I will test myself for a year then get x-rays done again a by nhs and then?????
Debby Owen says
I was taking generic Celebrex, which I purchased from a Canadian drug store as it was too expensive to buy here in the US, for arthritis. I still had a lot of pain. I’ve been taking CBD oil for over a year now and no longer take any other pain medicine for my arthritis. It really does work!!
Carly Fraser says
That’s a great testimony to the powers of CBD!
Bianca says
Which brand of CBD ARE YOU USING
does it have THC in it? What amount do you take ??
Carly Fraser says
Most CBD products do come with a small percentage of THC, but not enough to notice anything. I usually take at least 1000mg/mL, and then take according to what the bottle suggests. Look for organic brands like The Organic Dutchman (which I don’t think they have anything out yet, but they should soon).
Debbie says
Can anyone explain why even 2 drops of oil or tiny amount of ointment give me bad hot flashes during the night? So frustrating!
Carly Fraser says
Odd, I’ve never heard of that before. Maybe it’s a detox effect? Or maybe that is just too much? Have you tried taking it at any other time of the day?
Debbie says
I usually take in the am, will try right before bed. I use a very well researched product by my chiropractor, low dose. I hadn’t used any in weeks, did 2 drops yesterday and bam last night. No one has heard of this reaction.
Carly Fraser says
Yeah that is odd – I have never hear dof it either! I would say try it in the day and see if you get the same reaction. Sorry I can’t be of more help!