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Category: > Remedies > What Are the Health Benefits of Soursop (Graviola)?
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What Are the Health Benefits of Soursop (Graviola)?

Apr 13, 2025 Carly Fraser Post contains aAffiliate links Save For Later Print

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freshly cut soursop next to a glass of soursop juice

Soursop (Graviola) has been gaining attention as a tropical fruit with more than just a delicious taste. Known for its striking green spiky skin and tangy flavor, it’s quickly becoming a favorite in health and wellness circles—not just for its taste, but for its impressive potential health benefits. Among these, soursop’s cancer-fighting properties have sparked particular interest, but its wellness advantages go far beyond that.

For centuries, soursop has been a staple in traditional medicine, and modern health experts are now taking note. Rich in essential nutrients, this powerful fruit is believed to help support the immune system, reduce inflammation, and improve digestion, making it a great addition to your health routine.

So, what exactly are the health benefits of soursop? Let’s dive into its powerful potential and explore how this tropical fruit can support your journey to better health.

What is Soursop?

Soursop, scientifically known as Annona muricata, is a tropical fruit native to Central and South America, Southeast Asia, and the Caribbean. It features a spiky green outer skin with soft, white pulp that has a custard-like texture and a sweet, tangy flavor. Often used in smoothies, juices, and desserts, soursop is not just a tasty treat—it also has a rich history in traditional medicine. Indigenous cultures have long turned to this fruit for its medicinal properties, using various parts of the soursop tree to treat ailments like fever, infections, and inflammation.

While soursop is well-known for its role in natural remedies, it has only recently gained widespread attention in modern health and wellness circles due to its reported cancer-fighting capabilities. Let’s dive into the science and benefits behind this tropical powerhouse.

What Are the Health Benefits of Soursop?

While soursop’s cancer-fighting properties are a major highlight, this superfruit offers many other health benefits that can contribute to overall wellness. Let’s explore how soursop can support your health in various ways.

1. Soursop’s Role in Fighting Cancer: What the Science Says

Cancer is a life-changing diagnosis that affects millions of people around the world. While traditional treatments like chemotherapy and radiation are the standard, many people are looking to natural remedies to complement these treatments or even prevent cancer in the first place. Soursop has caught the attention of both researchers and health enthusiasts for its potential to help in the fight against cancer.

Several studies have shown that soursop contains compounds called acetogenins, which have demonstrated anti-cancer properties in laboratory settings. These acetogenins are believed to inhibit the growth of cancer cells, particularly those associated with breast, colon, liver, and pancreatic cancers. Unlike traditional treatments, which can damage healthy cells along with cancer cells, soursop may target only the cancerous cells, offering a more selective form of treatment.

In 1976, the National Cancer Institute (NCI) first identified the anti-cancer potential of graviola (also known as soursop) leaves. Their internal research stated: “The NCI, or the National Cancer Institute, conducted studies on the guanabana cancer cure [sic] and came up with some interesting results. The study… showed that the leaves and stems of the plant were incredibly efficient at destroying certain cancerous cells in the body.” While this study was never publicly released, follow-up research conducted at Purdue University produced similarly promising results.

At Purdue, much of the focus centered on annonaceous acetogenins—powerful compounds found in graviola. Researchers Oberlies, Chang, and McLaughlin discovered that these compounds were particularly effective against multi-drug resistant (MDR) tumor cells—cells that have developed resistance to a broad spectrum of chemotherapy drugs (1✓)✓ Trusted ResourcePubMed CentralHighly respected database from the National Institutes of HealthRead source. MDR cells require high levels of adenosine triphosphate (ATP), the cell’s primary energy source, to pump out chemotherapy agents. Acetogenins effectively inhibit ATP transfer within these cells, disrupting their function and leading to cell death.

The mechanism of graviola’s acetogenins is highly selective, targeting only cancerous cells while leaving healthy ones unharmed. This is because cancer cells exhibit significantly higher metabolic activity and ATP production, making them more recognizable to acetogenins. This selectivity is a major advantage over conventional chemotherapy, which indiscriminately attacks both cancerous and healthy cells—often leading to debilitating side effects like nausea, hair loss, and overall diminished quality of life. Graviola’s ability to focus solely on malignant cells presents a compelling alternative with far fewer side effects.

While more research is needed to fully understand how soursop works in cancer treatment, these early findings are promising. By incorporating soursop into a balanced diet, some believe it could play a role in both preventing cancer and supporting the body during treatment.

The Mechanisms Behind Its Cancer-Fighting Effects

The science behind soursop’s potential cancer-fighting effects is still evolving, but several key mechanisms have been identified (2✓)✓ Trusted ResourcePubMed CentralHighly respected database from the National Institutes of HealthRead source:

  • Selective Cytotoxicity: Soursop has been shown to selectively target cancer cells without harming healthy cells. This is due to its high concentration of acetogenins, which disrupt the energy production in cancer cells.
  • Antioxidant Properties: The antioxidants in soursop help neutralize harmful free radicals in the body, reducing oxidative stress and lowering the risk of cancer cell formation.
  • Immune System Support: Soursop is rich in vitamin C and other compounds that can enhance the immune system, helping the body fight off disease, including cancer.

While these findings are exciting, it’s important to remember that soursop should not replace conventional cancer treatments. Instead, it can be used as part of a holistic approach to health and well-being.

2. Boosts Immune System Function

Soursop is a rich source of vitamin C, a powerful antioxidant that supports immune health. Vitamin C helps stimulate the production of white blood cells, which are essential for fighting infections (3✓)✓ Trusted ResourcePubMed CentralHighly respected database from the National Institutes of HealthRead source. Regular consumption of soursop can give your immune system the boost it needs to ward off colds, flu, and other illnesses.

In addition to vitamin C, soursop also contains other immune-supporting nutrients like vitamin B1 (thiamine), which is necessary for maintaining a healthy immune response (4✓)✓ Trusted ResourcePubMed CentralHighly respected database from the National Institutes of HealthRead source. Soursop’s ability to strengthen the immune system makes it an excellent fruit for those looking to improve their body’s defense mechanisms.

4. Anti-inflammatory and Antioxidant Properties

Chronic inflammation is a root cause of many diseases, including arthritis, cardiovascular disease, and certain cancers. Soursop’s potent anti-inflammatory compounds can help reduce inflammation in the body, offering relief from conditions like joint pain and swelling (5✓)✓ Trusted ResourcePubMed CentralHighly respected database from the National Institutes of HealthRead source.

The fruit’s antioxidants, including vitamin C and flavonoids, also help combat oxidative stress, which can damage cells and tissues. By reducing inflammation and neutralizing free radicals, soursop helps protect your body from premature aging and chronic diseases.

5. Digestive Health

Soursop is known for its positive effects on digestive health. The fruit contains dietary fiber, which aids in digestion by promoting regular bowel movements and preventing constipation. Fiber also supports the growth of beneficial gut bacteria, contributing to a healthy microbiome.

In addition to fiber, soursop contains enzymes that help break down food and improve nutrient absorption. This makes it an excellent choice for supporting digestive health, especially for those with sensitive stomachs or digestive issues (6✓)✓ Trusted ResourcePubMed CentralHighly respected database from the National Institutes of HealthRead source.

6. Pain Relief and Stress Reduction

Soursop has been traditionally used to alleviate pain and promote relaxation. The fruit contains compounds that have mild sedative effects, which can help reduce stress and anxiety. Some studies suggest that soursop may help lower blood pressure, contributing to a sense of calm and relaxation (7✓)✓ Trusted ResourcePubMed CentralHighly respected database from the National Institutes of HealthRead source.

Additionally, soursop’s ability to act as a natural pain reliever makes it beneficial for individuals suffering from chronic pain conditions, such as arthritis or muscle soreness.

How to Incorporate Soursop Into Your Diet

If you’re ready to experience the health benefits of soursop, there are several ways to incorporate this fruit into your daily routine. Here are a few ideas:

1. Fresh Soursop Fruit

If you’re lucky enough to live in a region where soursop is available fresh, you can enjoy the fruit on its own. Simply cut open the spiky green skin to reveal the soft, white pulp inside. You can scoop out the flesh and eat it directly or mix it with other fruits in a tropical fruit salad.

2. Soursop Juice or Smoothies

One of the most popular ways to consume soursop is by blending it into a refreshing juice or smoothie. You can combine soursop pulp with water, coconut milk, or fruit juice for a delicious, nutrient-packed drink. Adding a little lime or ginger can enhance the flavor and offer additional health benefits.

3. Soursop Supplements

If fresh soursop is not available in your area, you can still benefit from its health properties by taking supplements. Soursop is available in various forms, including capsules, powders, and extracts. Be sure to consult with your healthcare provider before adding supplements to your routine to ensure they’re right for you.

4. Soursop Tea

Soursop leaves can also be used to make herbal tea. To prepare soursop leaf tea, steep dried soursop leaves in hot water for 10-15 minutes. This tea is often consumed for its calming effects and may also offer benefits for your immune system and digestive health.

Where to Buy Soursop

If you’re ready to incorporate soursop into your diet but aren’t sure where to find it, don’t worry! While soursop is most commonly found in tropical regions, there are several ways you can purchase it, whether fresh, frozen, or in supplement form. Here’s where you can look for this amazing fruit:

1. Local Farmers’ Markets (If Available)

If you live in a tropical or subtropical region, you might find fresh soursop at local farmers’ markets or produce stands. These markets often offer a variety of exotic fruits, and soursop may be available when in season. Buying fresh from a farmer’s market ensures you’re getting a ripe, high-quality fruit, often straight from the grower.

2. Specialty Grocery Stores and Health Food Stores

Certain grocery stores, especially those that focus on international or health foods, may carry fresh or frozen soursop. Stores like Whole Foods, Sprouts, and other specialty retailers with a focus on tropical fruits are good places to check for fresh or frozen soursop. If you can’t find it fresh, look for frozen soursop pulp, which can be easily used in smoothies, juices, and desserts.

3. Online Retailers

For those who don’t live near a tropical area, purchasing soursop online is a convenient option. There are a variety of online marketplaces that offer soursop in different forms:

  • Amazon: A great place to find frozen soursop pulp, soursop powder, or even soursop supplements like capsules and extracts.
  • eBay: Another option for purchasing fresh or frozen soursop, although availability can vary based on your location.
  • Specialty Health Food Websites: Sites like iHerb or Vitacost may offer soursop supplements, including dried leaves, powder, or concentrated extracts. Amafruits offers graviola pureé that can. be purchased online.

Just be sure to read customer reviews and check the seller’s credibility to ensure the product is of good quality.

4. Latin American and Caribbean Grocery Stores

If you live in an area with a large Latin American or Caribbean community, check out local grocery stores that specialize in products from these regions. These stores often carry fresh tropical fruits like soursop, as it’s a common ingredient in many Latin American and Caribbean cuisines and traditional medicine.

5. Ethnic or International Markets

Soursop can also be found in Asian, African, and Indian grocery stores that specialize in exotic fruits. Depending on where you’re located, visiting an international market could be your best bet for finding fresh or frozen soursop. Larger cities often have international markets that carry a wide variety of tropical fruits.

6. Soursop Supplements and Extracts

If you’re unable to find the fruit itself, soursop is widely available in supplement form. You can find soursop leaf extract, capsules, and powders at most health food stores or online. These supplements can provide many of the same health benefits as the whole fruit, especially when you’re looking to incorporate it into your routine for specific health purposes like immune support or digestive health.

Tips for Buying Soursop

  • Freshness Matters: If you’re purchasing fresh soursop, choose one that’s slightly soft to the touch, indicating it’s ripe. Avoid fruits with overly firm spots or visible damage.
  • Frozen vs. Fresh: While fresh soursop is ideal, frozen pulp is a great alternative, especially if fresh options aren’t available. It retains most of the fruit’s nutrients and can be used just like fresh soursop in smoothies, juices, and recipes.
  • Look for Organic Options: If possible, opt for organic soursop to avoid pesticides and chemicals often used in conventional farming. Organic options are available both in stores and online.

Risks and Considerations

While soursop offers many health benefits, it’s important to be aware of potential risks. For instance, excessive consumption of soursop or soursop supplements can lead to side effects, including nervous system toxicity.

Naturopath Leslie Taylor, author of The Healing Power of Rainforest Herbs acknowledges that alkaloids are highest in the seeds and roots of graviola and because of this, have shown neurotoxic effects in tests. She recommends, instead, using the leaves and pulp of the fruit when trying to treat certain illnesses (which is beneficial considering the leaves contain the highest concentration of acetogenins). Pregnant women should not consume large amounts of this fruit or the leaves, barks, or seeds, as the fetus produces large amounts of ATP, thus acetogenins could attack the developing fetus.

If you have any preexisting health conditions or are taking medications, be sure to consult with your healthcare provider before incorporating soursop into your routine.

The Bottom Line

Soursop, or Graviola, is more than just a delicious fruit—it’s a powerhouse of health benefits. From its potential to fight cancer to its ability to boost immunity, reduce inflammation, and improve digestion, soursop is an excellent addition to any health-conscious lifestyle.

While research is ongoing, the evidence so far suggests that soursop can play a supportive role in both preventing and managing various health conditions. As with any natural remedy, it’s important to use soursop as part of a holistic approach to health, incorporating it alongside other healthy habits like regular exercise and a balanced diet.

Whether you choose to enjoy soursop fresh, in smoothies, or as a supplement, make sure to consult with a healthcare provider to ensure it’s right for you. By adding soursop to your wellness routine, you’re taking a step toward better health and vitality.

This post contains affiliate links

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Filed Under: Food Education, Natural Therapies, Remedies Tagged With: Cancer, graviola, soursop

Carly Fraser

About the Author

Carly Fraser has her BSc (Hons.) Degree in Neuroscience, and is the owner and founder at Live Love Fruit. She currently lives in Winnipeg, Manitoba, with a determined life mission to help inspire and motivate individuals to critically think about what they put in their bodies and to find balance through nutrition and lifestyle. She has helped hundreds of thousands of individuals to re-connect with their bodies and learn self-love through proper eating habits and natural living. She loves to do yoga, dance, and immerse herself in nature.

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Comments

  1. Matalina says

    May 8, 2018 at 7:18 pm

    I think its really helpful with what Iam seeing and experiencing it. I have a elder sister and was with her for a week and came back to work. Just this morning after a week at work and received call that she is recovering slowly and some improvement in her sickness. Need to continue for another 2 – 3 weeks before she is fully recover. Thanks to the mother nature..for God's Glory.

    Reply
  2. Jody says

    Jul 8, 2018 at 11:55 am

    Hi Carly, thanks for this article. I have a fibroid and in my search I've discovered that soursop and bitter melon are two herbs that help shrink fibroids. Now my battle is to find these. I'm in Kelowna and don't have a big Asian market like T&T (one thing about Edmonton I miss). In the markets do they sell the leaves as well as the fruit? I have more research to do of course. Mahalo.

    Reply
    • Carly Fraser says

      Jul 9, 2018 at 9:09 am

      Hey Jody – I am pretty sure you can order online! I reference where you can buy in this article 🙂 I do not believe they sell the leaves as well as the fruit – I have never seen that. Maybe in the tea/herb section?

      Reply
      • Jody says

        Jul 9, 2018 at 9:17 am

        Thanks for your response. I found supplements yesterday and am starting today. Here's hoping…

        Reply
  3. munene says

    Oct 25, 2018 at 8:51 am

    Wonderful information.

    Reply
  4. Matt says

    Mar 6, 2019 at 3:10 pm

    Hi, is this safe to take with GERD ? Many thanks.

    Reply
    • Carly Fraser says

      Mar 6, 2019 at 8:33 pm

      Yes! Just make sure it is eaten on an empty stomach if you’re eating the fruit. Fruit should not be combined close with other hard to digest foods.

      Reply
  5. Joy says

    May 26, 2023 at 12:19 pm

    Is it safe to eat if you are on dialysis

    Reply
    • Carly Fraser says

      May 31, 2023 at 6:07 pm

      I’d ask your doctor!

      Reply
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