Injection Vs. Ingestion: Synergistic Toxicity and Vaccine Safety


Synergistic-toxicity-vaccine Certainly if you are on the front-lines of the vaccine debate you’ve heard the argument from pro vaxxers ‘hey well, y’know, a can of tuna has about the same amount of mercury in it that a vaccine does.’  Or about aluminum, ‘a muffin has as much aluminum as a vaccine containing aluminum’.  It is a silly argument but it shows you the mindset of some of these people that don’t question and research the very vaccine inserts or information available to them before they are injected.

First of all, anyone with a basic knowledge of biology should know the difference between injection and ingestion, one goes to the bloodstream, the other to the GI Tract.  Biologically they are much different, and that should end the argument right there with just simple biological logic. Let’s go a little deeper but also try and keep it simple.

Thimerosal is a vaccine preservative and well known neurotoxin (1) which is 49.55% mercury by weight (56.73% “Ethylmercury (etHg)” by weight).

When ingested, most of the mercury in tuna does not enter the body, but passes out in the stool. The mercury that does absorb is metabolized as methylmercury (meHG). Absorbing through the gut, first through the liver. This is called “First Pass”. The mercury going through the liver is conjugated by glutathione, then that conjugated glutathione is passed out in bile and then the stool.

When injected it is metabolized (converted) into the more toxic and harmful methylmercury.  Because it is injected, it avoids the ‘first pass’ through the liver where it could be filtered, instead it circulates throughout all the other tissues and organs. Mercury has a high affinity (binds well with) certain tissues, including neurological tissue, brain, kidneys, etc. So, in short then, the most harmful, long-term-toxic mercury is retained in the bodily tissue (Dr. Paul G. King).  Anyone can look up bio-accumulation of mercury in the body and the half life,  It’s not pretty.

In real life the toxic effect of both ingestion and injection of both types, ‘etHg and meHg combined, might result in enhanced neurotoxic effects.’  But studies seem to indicate ‘knowledge on this subject is still incomplete, and more is required to address the predictability of the additive or synergistic toxicological effects of etHg and meHg (or other neurotoxicants).’ (1a)

The pro vaccine advocate will usually try and confuse you at this point with some sort of misdirection blather about how either one of these, methylmercury or ethylmercury, are perfectly safe and/or that they are harmless and pass through safely no matter what the circumstance.  The FDA disagrees, in fact they say they:
“lack definitive data on the comparative toxicities of ethyl- versus methylmercury, they considered ethyl- and methyl-mercury as equivalent in its risk evaluation. There are some data and studies bearing directly on thimerosal toxicity and these are summarized in this section.” (2)

The CDC says “Is thimerosal safe for people? Yes. Thimerosal has been used safely in vaccines for a long time (since the 1930s) and has a proven track record of being safe. A variety of scientists have been studying the use of vaccines that have thimerosal in them for many years. They haven’t found any actual evidence that thimerosal causes harm.” (3)

It’s certainly easy not to find any evidence if you aren’t looking for it.  No safety studies were ever done by our health agencies and yet it was used on the public since the 1930’s. There is no proven track record ‘with studies’ of it being safe, no studies so ‘no scientists have been studying it’ unless they just didn’t publish their findings or unless studies were funded by big pharma hearings on thimerosol: (2 min).   I guess the CDC should talk to the FDA, NIH, etc.  There’s a good reason why the 3 year investigation by the government led to it’s final removal from ‘some’ vaccines (4).

Further, “(mercury) injection is distributed primarily in the central nervous system, kidneys, liver, and skin. Mercury crosses the blood brain barrier and the placenta; infants and the fetus are the most at risk for toxicity to occur. Mercury exposure by expecting mothers has been shown to cause neurological abnormalities. Infants exposed in utero to mercury have shown developmental delays. In addition, the possibility of a link between mercury exposure and neurological disorders such as autism and attention deficit hyperactivity disorder has been evaluated. Concentrations of thimerosal in vaccines and immunoglobulins range between 0.005 and 0.02%, a non-toxic concentration. However, a concern exists, not from exposure to a single vaccine, but that over a relatively short time span, children can be exposed to multiple vaccinations containing thimerosal. This repeated exposure might put children at risk for mercury toxicity.” (5)

The FDA has admitted that the safety of Thimerosal, when used as a preservative, has not been established to the regulatory standard, “sufficiently nontoxic… .” (6) This fact was established in a three-year investigation by a United States House Committee and set forth in the “A. Findings” section of its published 2003 report as set forth in Title 21 of the United States Code of Federal Regulations (21 CFR) at paragraph 610.15(a)[21 CFR § 610.15(a)]. (7)

The problem is the House Committee study only looked into the effects of a single product, not the effect of multiple products (many different vaccines over a short period of time).  There are no studies showing the safety of mixing different heavy metals such as Al (Aluminum) and Thimerosal. There are physical studies of mercury and aluminum in open air experiments which show rapid oxidative stress and violent reactions.  No tests have been done on what happens when these elements meet together in let’s say the brain or organs.

The literature that comes with most vaccines admits that … ‘has not been evaluated for its carcinogenic or mutagenic potential, or its potential to impair fertility.’

The fluval vaccine warns ‘safety and efficacy has not been established in pregnant women’ and yet it continues to be recommended to them.  So what happens when all these substances are mixed?

Image Sources: 1st box, page 4; 2nd box, page 7, section 13.1; 3rd box, page 7; 4th box, page 3; 5th box, page 18


Synergistic Toxicity

And that brings us to consider synergistic toxicity, that is the combining of more than one toxic substance in a cocktail to be injected and the dangers that entails.

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Image via

Safeminds explains:

“…when exposed to two toxins [or more], the toxicity level is far greater than the additive toxicity levels of the two toxins.” (8)

A good example demonstrating ‘synergistic toxicity’ is a 1978 study on mice (Shubert et al. Combined Effects in Toxicology – A Rapid systematic Testing Procedure: Cadmium, Mercury & Lead. J. of Toxicology & Environmental Health 4:763, 1978). The study took the amount of mercury salt that kills 1 in 100 mice and 1/20th of the amount of lead salt that kills 1 in 100 mice. When these amounts of mercury salt and lead salt were administered, the synergistic toxicity of these two toxins killed 100 in 100 mice:”

“If Additive toxicity, one would expect 1 + 0.05 = 1.05 mice to die (1 or 2)”

“With Synergistic toxicity, the results were: 1 + 0.05 = 100 mice died” (9)

And further “There is significant potential for unexpected ‘synergistic toxicity’ effects from vaccines, particularly for a susceptible population that may already have high toxin levels due to a lessened ability to excrete toxins. Yet synergistic toxicity of vaccines has not been studied – studies have focused on only individual toxicity of a single component of the vaccines (e.g. mercury or measles virus).” (10) [Emphasis mine]

Out of all the vaccine debates I have watched since my research on vaccines began back in 2009 I have yet to hear synergistic toxicity brought up once.  This seems acutely important and integral to the debate. Certainly Aluminum is toxic as well, as I will show later.  Some other toxicity studies, many suggesting the pressing need for synergistic toxicity studies. (11) (12) (13) (14)

So, let’s get this straight, thimerosal was never tested by any of our health agencies and was used in vaccines anyway from the 1930’s (and still in some), and finally removed from most because of public outcry and then the government began to study it and decided yes, it’s probably not safe (see footnotes above).  The same will likely happen with Aluminum in 20-30 years after the public outcry again, but how many children and people will have had to suffer until then? Again, Short 2 minute video clip of Hearings on Thimerosal.

Pro vaxxers say “Ah but there’s no Thimerosal in vaccines anymore!” It’s interesting to note is that of the few vaccines that is given to infants that still hast himerosal in it is Hep B and DipTet (and Flu shot that is recommended to mothers now).  So, the claim that it has been removed from all vaccines is a lie and misdirection. If they give it to all newborns then all the newborns are getting that thimerosal. “It was removed from many child vaccines in 2002 but remains in some vaccines (e.g., hepatitis B virus and influenza).” (15)  And they get multiple doses of different cocktails.

Other studies suggest there is an increase in fetal death (demise) reporting rates in the VAERS database relative to the reported annual trends. Thus, a synergistic fetal toxicity likely resulted (from multiple combined exposures) (16) as well as many other findings show “a positive correlation between the number of vaccine doses administered and the percentage of hospitalizations and deaths. Since vaccines are given to millions of infants annually, it is imperative that health authorities have scientific data from synergistic toxicity studies on all combinations of vaccines that infants might receive. Finding ways to increase vaccine safety should be the highest priority.” (17)

Further, “ethylmercury (EtHg) and adjuvant-Al (aluminum) are the dominating interventional exposures encountered by fetuses, newborns, and infants due to immunization with Thimerosal-containing vaccines (TCVs). Despite their long use as active agents of medicines and fungicides, the safety levels of these substances HAVE NEVER BEEN DETERMINED, either for animals or for adult humans—much less for fetuses, newborns, infants, and children … the potential synergistic effect of both toxic agents has not been properly studied. Therefore, early life exposure to both etHg and Al deserves due consideration.” (18)

Synergistic Carcinogenic and Mutagenic Potential

So what about the effects of all the other ingredients in vaccines, such as aborted fetal cell lines, formaldehyde, DNA from other species such as monkeys, chickens, guinea pigs, etc? Well, no one knows! None have been evaluated for their carcinogenic or mutagenic potential individually or combined (synergistic toxicity), or its potential to impair fertility, and they say so right on the instructions/box!

Vaccines that have been cultured on or manufactured using the WI-38 fetal cell line such as MeruvaxII®, MMRII®, Varivax®, Havrix® and Pentacel® are additionally contaminated with fragments of human endogenous retrovirus HERVK (Victoria et al., 2010). Recent evidence has shown that human endogenous retroviral transcripts are elevated in the brains of patients with schizophrenia or bipolar disorder (Frank et al., 2005), in peripheral blood mononuclear leucocytes of patients with autism spectrum (Freimanis et al., 2010) as well as associated with several autoimmune diseases (Tai et al., 2008). The strong ecological association between human fetal cell line-manufactured vaccines and autistic disorder change points calls for further investigation of these childhood vaccine contaminants. (19) (20) (21)

These are already considered a biohazard before being used to propagate a virus for use in a vaccine. ‘WARNINGS AND PRECAUTIONS: Cell culture products can transmit infectious agents. Products should be handled in accordance with the CDC-NIH manual, Biosafety in Microbiological and Biomedical Laboratories, 2007.’  (22)

The vaccines below were developed using either the WI-38 or the MRC-5 cell strains. This list is not exhaustive:

– Hepatitis A vaccines [VAQTA/Merck, Havrix/GlaxoSmithKline, and part of Twinrix/GlaxoSmithKline]
– Rubella vaccine [MERUVAX II/Merck, part of MMR II/Merck, and ProQuad/Merck]
– Varicella (chickenpox) vaccine [Varivax/Merck, and part of ProQuad/Merck]
– Zoster (shingles) vaccine [Zostavax/Merck]
– Adenovirus Type 4 and Type 7 oral vaccine [Barr Labs]
– Rabies vaccine [IMOVAX/Sanofi Pasteur]

Summing Up

As you can probably tell, the Can of Tuna Argument is moot at this point, and as you continue reading the studies below you’ll begin to see even clearer why.  They can’t hide the fact that these substances are toxic even at low doses, and especially in multiple doses.  Considering the other factors such as synergistic toxicity, synergistic carcinogenic potential and the Government’s own findings (as well as studies below) we can put that lame argument to rest.  The Vaccine Injury Compensation Program has paid out over $3.1 billion dollars to vaccine injury/death claims so far, when will they admit that they are not safe?  Even the Supreme Court had to admit that vaccines were in a category of ‘unavoidably unsafe’ products. (23)

The real question now is, after all the government hearings, findings and studies, why is thimerosal, or aluminum still being used at all and even in combination with each other as well as all the other additives? And why do our health Czars keep lying to us?

Check out my other popular research link: ‘Why Are We Still Vaccinating? Questions From A Former Pro-Vaccine Advocate.’

1. Thimerosol in Vaccines:
2. FDA Blood Biologics:
6. The relevant portion of 21 CFR § 610.15(a), an explicit binding requirement on all manufacturers of biological drug products, including vaccines, states (emphasis added),“ Any preservative used shall be sufficiently nontoxic so that the amount present in the recommended dose of the product will not be toxic to the recipient.”
7. “Mercury in Medicine–Taking Unnecessary Risks, A Report Prepared by the Staff of the Subcommittee on Human Rights and Wellness, Committee on Government Reform United States House of Representatives, Chairman Dan Burton, May 2003 (This Report Is the Result of a Three Year Investigation Initiated in the Committee on Government Reform)”, which was also published in the Extended Congressional Record, May 21, 2003 CONGRESSIONAL RECORD—Extensions of Remarks, pages E1011-E1030; the relevant finding is disclosed in column 3 of page E1012 (emphasis added). “3.Manufacturers of vaccines and thimerosal, (an ethylmercury compound used in vaccines), have never been tested…
9. Ibid
10. Ibid
15. (Page 21)

– Many More Studies Here
– A ‘must read’. Mercury in Medicine–Taking Unnecessary Risks
– A Report Prepared by the Staff of the Subcommittee on Human Rights and Wellness Committee on Government Reform. United States House of Representatives, May 2003. (This Report Is the Result of a Three Year Investigation Initiated in the Committee on Government Reform.)



Brian is a freelance writer and researcher in the area of holistic health. He administers several health pages and has been published in various publications such as and has a keen interest in naturopathic healing through alternative medicine, such as essential oils as well as nutritional healing. He loves hiking, the outdoors, getting out in nature. He lives on the outskirts of Eugene, Oregon.


  1. Is there a typo in the first sentence of the 5th paragraph? Should it be "ethylmercury" instead of "methylmercury"? I would like to share this with someone, but cannot with what a appears to be a typo at a very bad place in understanding the article.

    • Sorry about that Emily! Maybe the author can clear up the confusion? Seems like he talks about both ethyl and methyl here, so not sure the exact sentence you are referring to..


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