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Category: > Remedies > What Are the Health Benefits of Soursop (Graviola)?
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What Are the Health Benefits of Soursop (Graviola)?

Apr 13, 2025 Carly Fraser Post contains aAffiliate links Save For Later Print

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freshly cut soursop next to a glass of soursop juice

Soursop (Graviola) has been gaining attention as a tropical fruit with more than just a delicious taste. Known for its striking green spiky skin and tangy flavor, it’s quickly becoming a favorite in health and wellness circles—not just for its taste, but for its impressive potential health benefits. Among these, soursop’s cancer-fighting properties have sparked particular interest, but its wellness advantages go far beyond that.

For centuries, soursop has been a staple in traditional medicine, and modern health experts are now taking note. Rich in essential nutrients, this powerful fruit is believed to help support the immune system, reduce inflammation, and improve digestion, making it a great addition to your health routine.

So, what exactly are the health benefits of soursop? Let’s dive into its powerful potential and explore how this tropical fruit can support your journey to better health.

What is Soursop?

Soursop, scientifically known as Annona muricata, is a tropical fruit native to Central and South America, Southeast Asia, and the Caribbean. It features a spiky green outer skin with soft, white pulp that has a custard-like texture and a sweet, tangy flavor. Often used in smoothies, juices, and desserts, soursop is not just a tasty treat—it also has a rich history in traditional medicine. Indigenous cultures have long turned to this fruit for its medicinal properties, using various parts of the soursop tree to treat ailments like fever, infections, and inflammation.

While soursop is well-known for its role in natural remedies, it has only recently gained widespread attention in modern health and wellness circles due to its reported cancer-fighting capabilities. Let’s dive into the science and benefits behind this tropical powerhouse.

What Are the Health Benefits of Soursop?

While soursop’s cancer-fighting properties are a major highlight, this superfruit offers many other health benefits that can contribute to overall wellness. Let’s explore how soursop can support your health in various ways.

1. Soursop’s Role in Fighting Cancer: What the Science Says

Cancer is a life-changing diagnosis that affects millions of people around the world. While traditional treatments like chemotherapy and radiation are the standard, many people are looking to natural remedies to complement these treatments or even prevent cancer in the first place. Soursop has caught the attention of both researchers and health enthusiasts for its potential to help in the fight against cancer.

Several studies have shown that soursop contains compounds called acetogenins, which have demonstrated anti-cancer properties in laboratory settings. These acetogenins are believed to inhibit the growth of cancer cells, particularly those associated with breast, colon, liver, and pancreatic cancers. Unlike traditional treatments, which can damage healthy cells along with cancer cells, soursop may target only the cancerous cells, offering a more selective form of treatment.

In 1976, the National Cancer Institute (NCI) first identified the anti-cancer potential of graviola (also known as soursop) leaves. Their internal research stated: “The NCI, or the National Cancer Institute, conducted studies on the guanabana cancer cure [sic] and came up with some interesting results. The study… showed that the leaves and stems of the plant were incredibly efficient at destroying certain cancerous cells in the body.” While this study was never publicly released, follow-up research conducted at Purdue University produced similarly promising results.

At Purdue, much of the focus centered on annonaceous acetogenins—powerful compounds found in graviola. Researchers Oberlies, Chang, and McLaughlin discovered that these compounds were particularly effective against multi-drug resistant (MDR) tumor cells—cells that have developed resistance to a broad spectrum of chemotherapy drugs (1✓)✓ Trusted ResourcePubMed CentralHighly respected database from the National Institutes of HealthRead source. MDR cells require high levels of adenosine triphosphate (ATP), the cell’s primary energy source, to pump out chemotherapy agents. Acetogenins effectively inhibit ATP transfer within these cells, disrupting their function and leading to cell death.

The mechanism of graviola’s acetogenins is highly selective, targeting only cancerous cells while leaving healthy ones unharmed. This is because cancer cells exhibit significantly higher metabolic activity and ATP production, making them more recognizable to acetogenins. This selectivity is a major advantage over conventional chemotherapy, which indiscriminately attacks both cancerous and healthy cells—often leading to debilitating side effects like nausea, hair loss, and overall diminished quality of life. Graviola’s ability to focus solely on malignant cells presents a compelling alternative with far fewer side effects.

While more research is needed to fully understand how soursop works in cancer treatment, these early findings are promising. By incorporating soursop into a balanced diet, some believe it could play a role in both preventing cancer and supporting the body during treatment.

The Mechanisms Behind Its Cancer-Fighting Effects

The science behind soursop’s potential cancer-fighting effects is still evolving, but several key mechanisms have been identified (2✓)✓ Trusted ResourcePubMed CentralHighly respected database from the National Institutes of HealthRead source:

  • Selective Cytotoxicity: Soursop has been shown to selectively target cancer cells without harming healthy cells. This is due to its high concentration of acetogenins, which disrupt the energy production in cancer cells.
  • Antioxidant Properties: The antioxidants in soursop help neutralize harmful free radicals in the body, reducing oxidative stress and lowering the risk of cancer cell formation.
  • Immune System Support: Soursop is rich in vitamin C and other compounds that can enhance the immune system, helping the body fight off disease, including cancer.

While these findings are exciting, it’s important to remember that soursop should not replace conventional cancer treatments. Instead, it can be used as part of a holistic approach to health and well-being.

2. Boosts Immune System Function

Soursop is a rich source of vitamin C, a powerful antioxidant that supports immune health. Vitamin C helps stimulate the production of white blood cells, which are essential for fighting infections (3✓)✓ Trusted ResourcePubMed CentralHighly respected database from the National Institutes of HealthRead source. Regular consumption of soursop can give your immune system the boost it needs to ward off colds, flu, and other illnesses.

In addition to vitamin C, soursop also contains other immune-supporting nutrients like vitamin B1 (thiamine), which is necessary for maintaining a healthy immune response (4✓)✓ Trusted ResourcePubMed CentralHighly respected database from the National Institutes of HealthRead source. Soursop’s ability to strengthen the immune system makes it an excellent fruit for those looking to improve their body’s defense mechanisms.

4. Anti-inflammatory and Antioxidant Properties

Chronic inflammation is a root cause of many diseases, including arthritis, cardiovascular disease, and certain cancers. Soursop’s potent anti-inflammatory compounds can help reduce inflammation in the body, offering relief from conditions like joint pain and swelling (5✓)✓ Trusted ResourcePubMed CentralHighly respected database from the National Institutes of HealthRead source.

The fruit’s antioxidants, including vitamin C and flavonoids, also help combat oxidative stress, which can damage cells and tissues. By reducing inflammation and neutralizing free radicals, soursop helps protect your body from premature aging and chronic diseases.

5. Digestive Health

Soursop is known for its positive effects on digestive health. The fruit contains dietary fiber, which aids in digestion by promoting regular bowel movements and preventing constipation. Fiber also supports the growth of beneficial gut bacteria, contributing to a healthy microbiome.

In addition to fiber, soursop contains enzymes that help break down food and improve nutrient absorption. This makes it an excellent choice for supporting digestive health, especially for those with sensitive stomachs or digestive issues (6✓)✓ Trusted ResourcePubMed CentralHighly respected database from the National Institutes of HealthRead source.

6. Pain Relief and Stress Reduction

Soursop has been traditionally used to alleviate pain and promote relaxation. The fruit contains compounds that have mild sedative effects, which can help reduce stress and anxiety. Some studies suggest that soursop may help lower blood pressure, contributing to a sense of calm and relaxation (7✓)✓ Trusted ResourcePubMed CentralHighly respected database from the National Institutes of HealthRead source.

Additionally, soursop’s ability to act as a natural pain reliever makes it beneficial for individuals suffering from chronic pain conditions, such as arthritis or muscle soreness.

How to Incorporate Soursop Into Your Diet

If you’re ready to experience the health benefits of soursop, there are several ways to incorporate this fruit into your daily routine. Here are a few ideas:

1. Fresh Soursop Fruit

If you’re lucky enough to live in a region where soursop is available fresh, you can enjoy the fruit on its own. Simply cut open the spiky green skin to reveal the soft, white pulp inside. You can scoop out the flesh and eat it directly or mix it with other fruits in a tropical fruit salad.

2. Soursop Juice or Smoothies

One of the most popular ways to consume soursop is by blending it into a refreshing juice or smoothie. You can combine soursop pulp with water, coconut milk, or fruit juice for a delicious, nutrient-packed drink. Adding a little lime or ginger can enhance the flavor and offer additional health benefits.

3. Soursop Supplements

If fresh soursop is not available in your area, you can still benefit from its health properties by taking supplements. Soursop is available in various forms, including capsules, powders, and extracts. Be sure to consult with your healthcare provider before adding supplements to your routine to ensure they’re right for you.

4. Soursop Tea

Soursop leaves can also be used to make herbal tea. To prepare soursop leaf tea, steep dried soursop leaves in hot water for 10-15 minutes. This tea is often consumed for its calming effects and may also offer benefits for your immune system and digestive health.

Where to Buy Soursop

If you’re ready to incorporate soursop into your diet but aren’t sure where to find it, don’t worry! While soursop is most commonly found in tropical regions, there are several ways you can purchase it, whether fresh, frozen, or in supplement form. Here’s where you can look for this amazing fruit:

1. Local Farmers’ Markets (If Available)

If you live in a tropical or subtropical region, you might find fresh soursop at local farmers’ markets or produce stands. These markets often offer a variety of exotic fruits, and soursop may be available when in season. Buying fresh from a farmer’s market ensures you’re getting a ripe, high-quality fruit, often straight from the grower.

2. Specialty Grocery Stores and Health Food Stores

Certain grocery stores, especially those that focus on international or health foods, may carry fresh or frozen soursop. Stores like Whole Foods, Sprouts, and other specialty retailers with a focus on tropical fruits are good places to check for fresh or frozen soursop. If you can’t find it fresh, look for frozen soursop pulp, which can be easily used in smoothies, juices, and desserts.

3. Online Retailers

For those who don’t live near a tropical area, purchasing soursop online is a convenient option. There are a variety of online marketplaces that offer soursop in different forms:

  • Amazon: A great place to find frozen soursop pulp, soursop powder, or even soursop supplements like capsules and extracts.
  • eBay: Another option for purchasing fresh or frozen soursop, although availability can vary based on your location.
  • Specialty Health Food Websites: Sites like iHerb or Vitacost may offer soursop supplements, including dried leaves, powder, or concentrated extracts. Amafruits offers graviola pureé that can. be purchased online.

Just be sure to read customer reviews and check the seller’s credibility to ensure the product is of good quality.

4. Latin American and Caribbean Grocery Stores

If you live in an area with a large Latin American or Caribbean community, check out local grocery stores that specialize in products from these regions. These stores often carry fresh tropical fruits like soursop, as it’s a common ingredient in many Latin American and Caribbean cuisines and traditional medicine.

5. Ethnic or International Markets

Soursop can also be found in Asian, African, and Indian grocery stores that specialize in exotic fruits. Depending on where you’re located, visiting an international market could be your best bet for finding fresh or frozen soursop. Larger cities often have international markets that carry a wide variety of tropical fruits.

6. Soursop Supplements and Extracts

If you’re unable to find the fruit itself, soursop is widely available in supplement form. You can find soursop leaf extract, capsules, and powders at most health food stores or online. These supplements can provide many of the same health benefits as the whole fruit, especially when you’re looking to incorporate it into your routine for specific health purposes like immune support or digestive health.

Tips for Buying Soursop

  • Freshness Matters: If you’re purchasing fresh soursop, choose one that’s slightly soft to the touch, indicating it’s ripe. Avoid fruits with overly firm spots or visible damage.
  • Frozen vs. Fresh: While fresh soursop is ideal, frozen pulp is a great alternative, especially if fresh options aren’t available. It retains most of the fruit’s nutrients and can be used just like fresh soursop in smoothies, juices, and recipes.
  • Look for Organic Options: If possible, opt for organic soursop to avoid pesticides and chemicals often used in conventional farming. Organic options are available both in stores and online.

Risks and Considerations

While soursop offers many health benefits, it’s important to be aware of potential risks. For instance, excessive consumption of soursop or soursop supplements can lead to side effects, including nervous system toxicity.

Naturopath Leslie Taylor, author of The Healing Power of Rainforest Herbs acknowledges that alkaloids are highest in the seeds and roots of graviola and because of this, have shown neurotoxic effects in tests. She recommends, instead, using the leaves and pulp of the fruit when trying to treat certain illnesses (which is beneficial considering the leaves contain the highest concentration of acetogenins). Pregnant women should not consume large amounts of this fruit or the leaves, barks, or seeds, as the fetus produces large amounts of ATP, thus acetogenins could attack the developing fetus.

If you have any preexisting health conditions or are taking medications, be sure to consult with your healthcare provider before incorporating soursop into your routine.

The Bottom Line

Soursop, or Graviola, is more than just a delicious fruit—it’s a powerhouse of health benefits. From its potential to fight cancer to its ability to boost immunity, reduce inflammation, and improve digestion, soursop is an excellent addition to any health-conscious lifestyle.

While research is ongoing, the evidence so far suggests that soursop can play a supportive role in both preventing and managing various health conditions. As with any natural remedy, it’s important to use soursop as part of a holistic approach to health, incorporating it alongside other healthy habits like regular exercise and a balanced diet.

Whether you choose to enjoy soursop fresh, in smoothies, or as a supplement, make sure to consult with a healthcare provider to ensure it’s right for you. By adding soursop to your wellness routine, you’re taking a step toward better health and vitality.

This post contains affiliate links

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Filed Under: Food Education, Natural Therapies, Remedies Tagged With: Cancer, graviola, soursop

Carly Fraser

About the Author

Carly Fraser has her BSc (Hons.) Degree in Neuroscience, and is the owner and founder at Live Love Fruit. She currently lives in Winnipeg, Manitoba, with a determined life mission to help inspire and motivate individuals to critically think about what they put in their bodies and to find balance through nutrition and lifestyle. She has helped hundreds of thousands of individuals to re-connect with their bodies and learn self-love through proper eating habits and natural living. She loves to do yoga, dance, and immerse herself in nature.

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Comments

  1. Bhupen says

    Sep 29, 2012 at 4:44 pm

    Very good

    Reply
  2. AMAR AMBRE says

    Sep 29, 2012 at 6:47 pm

    hi…sir happy to read the research..yes these Pharma giants are much more dangerous to us..HUMANS then what CANCER is..!! i work for a nuk.power stn,i know what dangerous effects radiation causes to life..please many of us spread these natural medicines which are pushed back by the big pharama GIANTS…thnx to your research team sir n we all are with you…

    Reply
  3. George says

    Sep 29, 2012 at 7:53 pm

    The most effective things are bitter apricot seeds or almonds. Seriously. B17 people!

    Reply
    • Robin says

      Dec 16, 2012 at 1:34 am

      Your right about B17, however the USA banned B17 in the 1970’s.

      Reply
    • Sara Anton says

      Jul 5, 2016 at 12:31 am

      I did a full treatment of apricot kernels and my tumor kept growing. I measured it to track it. Finally had to turn to conventional medicine at which point I was found to be stage 4 cancer that had metastized to the bone.

      Reply
      • Francesca says

        Sep 22, 2016 at 8:48 pm

        I’m so sorry sara, I will keep you in my prayers

        Reply
      • Rosina Lock says

        Oct 27, 2016 at 6:26 pm

        Hi Sara, I am leaving a message for you babe, because you say you did a full treatment of the apricot kernels and the tumour kept growing? The reason could be babe, is that if your cancer is really terminal, then sometimes apricot kernals do not work? But it does for most? I am also replying to your message due to the fact that it is so up to date! Please Sara, do not lose hope babe! PLEASE WILL YOU TYPE IN:
        EARTH CLINIC: CANCER this is the most brilliant site I have been on for some years, you will get all the help you need babe! And this applies to all who are online! This is a site whereby over 3,500 cures have been made! When you log in just type earth clinic Cancer! On this particular subject you should find about 15 pages on cures from kitchen cupboards that are actually curing you of cancer! Please don’t laugh! I am serious! This site is about thousands of people coming online from all over the world, they state what they used, if it was a cure they will rate it as five, if dangerous they will state it just watch the reviews! When you get to the bottom of the people that have written what they tried, you will see page 2, 3 4, 5 etc, just click on to each page! Have a pen and paper handy and take notes! You will find your cure amongst these pages, just try anything and everything! These are people who care about others. I am a 70 year old lady (looking 40 lol) but I care about people. There are many simple cures out there Sara, if the apricot kernels didn’t work, go for another, but please! Try to stay away from chemotherapy and radiation treatment, they are a killer! I am wondering If you are in the USA? That means the FDA are blocking all cures! As is the Medical profession namely where I reside in the UK, hence Cancer Research.co.uk who have accused over 147 treatments as “quackery” I cannot believe the thousands of lives they have taken by using their horrific and barbaric treatment. This is all about the Pharmaceutical companies who don’t give a damn whether you live or die, please, if you value your life or have anyone ill, please go online to EARTH CLINIC; TYPE IN WHATEVER ILLNESS YOU HAVE! Thousands are online ready to help you. These are highly intelligent people from all over the world who are fighting back! They refuse to let the FDA or Cancer.co.uk take over their lives with their humiliating and useless treatment. Over 100 doctors have been murdered in the past 12 months! WHY? Because they have all found cures of cancer, etc.etc. and the FDA and the British Medical association are so obsessed with money! If you have a cure for cancer?
        The FDA or Cancer.co.uk will run them down, talking of the dangers! It is ludicrous. I have been researching for many years. Please if you value your life? Think of alternative cures, you will not find it by having chemotherapy or radiation treatment, in fact even if you have terminal cancer, you will live longer by not having this barbaric treatment. I am a 70 year old lady (yes, looking 40 lol) but I care about people, and if you think you can get a cure by even the most ridiculous treatment? You go for it. The government don’t own you! You owe it to yourself to get better. I need to go offline now, as I haven’t slept for almost 48 hours and I am very tired, but I sincerely wish you all the very best of luck. May I please say PLEASE WHATEVER CHOICE YOU CHOOSE? PLEASE RESEARCH OR TYPE IN: SIDE EFFECTS! THIS IS MOST IMPORTANT. I wish you all the best of health. Rosina Lock from East End of London, a lady on a mission. via facebook.

        Reply
        • Estee says

          Nov 28, 2016 at 11:40 am

          Thanks very helpful!!

          Reply
  4. Jo Ann says

    Sep 29, 2012 at 7:53 pm

    Ebay has the trees…….

    Reply
  5. Ryan Bollenbach says

    Sep 29, 2012 at 11:23 pm

    Carly,

    Based on the tendencies of improvement you’ve probably studied from other fruits and veg, does something like this seem possible?

    What are your thoughts on eating a plant as the source to cure something vs a concentrated version of it, made into medicine? (natural medicine – not pumped with a bunch of extra ingrediants).

    Thoughts?

    Reply
    • Carly Fraser says

      Sep 30, 2012 at 4:57 pm

      Yes, something like this definitely does seem possible.

      The variety of Amazonian fruits that the general public is not aware of just goes to show the incredible variety and unknown tendencies of these fruits and/or herbs. Most pharma-giants do not want anyone to know of them because it would essentially ruin their business. Every fruit is different with respect to antioxidant load and the different types of antioxidants they carry – and seeing as how these preliminary studies have shown such powerful results is really tempting – it would be curious to see how it would apply in humans, and it is also doubly curious how pharmaceutical companies, as we speak, are trying to patent the chemical in the fruit in order to make money off it (obviously they know that this fruit has potential for a cure).

      I believe that eating the plant straight up is going to be MUCH more beneficial than any pharmaceutical-manipulated compound from the fruit, or from a fruit juice that has been processed and heated, which destroys beneficial enzymes and antioxidants. As for turning it into a natural medicine, such as capsules, I would say it would be better than something a pharmaceutical has tried manipulating (since that would need a patent, and thus the chemical structure would need to be manipulated, and thus it would be a much less potent form). However, raw, as always, is best! Fresh fruit is always number one!

      Reply
      • Ryan Bollenbach says

        Oct 1, 2012 at 4:02 pm

        Cool, that makes sense and I can completely understand why people would want to go in business with this fruit.

        I was just thinking it could be even stronger if you were able to produce a concentrated extract of the fruit but raw and natural is probably more safe too.

        Reply
  6. Samuel Adanu says

    Oct 1, 2012 at 2:57 pm

    I can help anyone who needs the Soursop cancer killer fruit. It is widely grown in Ghana and it is normally harvested in season. Get in touch with me via my blog page if you need some.

    You might consider importing it into your country.

    Regards,

    Samuel.

    Reply
    • Tracy says

      Jan 10, 2013 at 1:47 pm

      Samuel
      could you pls email me pls with ur details pls ?
      very interested in maybe purchasing some plants
      thx regards Tracy
      [email protected]
      we have a very great friend of ours with cancer & would like 2 help him 🙂

      Reply
    • sandra says

      Apr 7, 2013 at 6:38 pm

      hi there maby you sell those fruts? or how you can help? tnkx

      Reply
      • Carly Fraser says

        Apr 13, 2013 at 2:42 pm

        Sorry I do not sell this fruit. Your local asian market should have them, or you could request they order it for you!

        Reply
    • sandra says

      Jun 25, 2013 at 3:44 am

      Could you please email me at [email protected] would like to make an order from Aus

      Reply
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